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diagnosis differential classification hemolytic management oncology common comparison cvid disorders extravascular hemolysis hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular leukemia lymphoma platelet
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Cold Urticaria Prevalence ... decades of life Causes ... fever, fatigue, Nausea ... infiltration (lymphocytes ... Urticaria #diagnosis #rheumatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
for Hemolytic Anemia ... : • Liver disease ... • AIHA: warm, cold ... #Hemolytic #Anemia ... classification #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... differential #diagnosis #hematology ... #anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
practices that could ... PT, aPTT(liver disease ... changes), high MCV anemia ... bypass), LFT (liver disease ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... HL (MCHL) - Lymphocyte ... number of sites of disease ... classification #hematology
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