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diagnosis oncology management algorithm chronic classification cll differential hodgkins lymphoma anemia aplastic biliary cancer cholangitis cirrhosis comparison disorders hemeonc heon
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... • Most common leukemia ... immunophenotype Clinical ... #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... with no early symptoms ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... B-cell lineage ALL Symptoms ... Leukemia): • Lymphocytes ... #Hematology #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
cells absent, lymphocyte ... Rich, Lymphocyte ... pattern of spread, B symptoms ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... involved) • No leukemic ... Noncontiguous spread • Clinical ... Lymphomas • Other hematologic ... #differential #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology: • T lymphocyte ... PBC Signs and Symptoms ... cholangitis #diagnosis #workup ... #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... ingestion • B symptoms ... HL (MCHL) - Lymphocyte ... Hodgkin Lymphoma Workup ... classification #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... virus (EBV) • Leukemia ... • Improve the symptoms ... Anemia #oncology #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
) - Clinical symptoms ... Diagnosis #Signs #Hematology ... #Workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... • Hairy Cell Leukemia ... Workup: • Complete ... Syndromes #diagnosis #hematology
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