11 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
QD (adjust dose at ... calcium for K; also binds ... nonspecifically binds ... #pharmacology #table ... #comparison #binders
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
Phosphate Binders ... ; may have ancillary ... ; may have ancillary ... pill burden - May ... #Table #Comparison
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #pharmacology #table ... #comparison #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Lower risk of hypercalcemia ... absorption of iron that may ... #Phosphate #Binders ... #Table #Comparison
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
Diagnostic algorithm ... the workup of hypercalcemia ... collection.44 Of note, at ... sensitivity for correct classification ... #Differential #Algorithm
Algorithm for Management of Acute and Chronic Hyperkalemia
Acute Hyperkalemia:
 - IV calcium (10 mL of 10%)
Algorithm for Management ... - Consider K+ binders ... bicarbonate - Consider binders ... (may facilitate ... #Algorithm #Management
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Lactated Ringers ... Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... excretion • Saline May ... Normal #Saline #NS #comparison
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antibodies bind to mast ... specific allergen binds ... or IgM antibody binds ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes mast-cell ... types #allergy #table ... #classification ... #comparison