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Pathophysiology of hypotonic hyponatremia

by Helbert Rondon, MD @NephroMD

#hypotonic #hyponatremia #nephrology #algorithm #Pathophysiology
Pathophysiology of hypotonic ... hyponatremia ... @NephroMD #hypotonic ... #hyponatremia # ... nephrology #algorithm
Hypo-osmolar Hypotonic HypoNatremia Algorithm (Serum Na+ < 135 meq/L, serum Osm < 275 mosm/kg)
Assess Volume Status,
Hypo-osmolar Hypotonic ... HypoNatremia Algorithm ... #Algorithm #Diagnosis ... #Nephrology #Differential ... #Hypotonic
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Algorithm Hypertonic ... Urologic irrigants Hypotonic ... #Algorithm #diagnosis ... #sodium #nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Algorithm Isotonic ... , Recent TURP Hypotonic ... polydipsia • Hypervolemia ... #Differential #Algorithm ... diagnosis #causes #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Hyponatremia The ... hyponatremia, give ... normal volume-based algorithm ... : Hypovolemia, Hypervolemia ... table #sodium #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... and Workup Step ... mmol/L - true hyponatremia ... #Diagnosis #Workup ... #Algorithm #Nephrology
Hyponatremia with Severe Symptoms - Management Algorithm with Hypertonic Saline
The goal of acute management is to
Hyponatremia with ... Symptoms - Management Algorithm ... with Hypertonic ... #treatment #Hypertonic ... #Saline #nephrology
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Differential Diagnosis Algorithm ... Hypocalciuric Hypercalcemia ... Differential #Diagnosis #Algorithm ... #Workup #nephrology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Diagnosis Algorithm ... Diabetes Insipidus Workup ... #Management #Algorithm ... #Sodium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... hormone secretion Hypervolemia ... renal failure Hypervolemia ... #Causes #nephrology