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differential management nephrology criticalcare rheumatology acidosis antinxp2 antinxp2dm challenges classification dermatology dermatomyositis diuresis diuretics elevation excretion fluid hyperkalemia hypertension hypoaldosteronism
Etiologies of Hypoaldosteronism Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone) - Diabetic Nephropathy - NSAIDs Non-Hyporeninemic Hypoaldosteronism (Normal
heparin - Primary adrenal ... insufficiency - Critical ... #Differential #Diagnosis ... #Comparison #Table ... #Causes
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
- Differential Diagnosis ... at 4 h of infusion ... CT or MRI scan of ... #Differential #Diagnosis ... #Workup #table
Shock - Differential Diagnosis Framework MAP = CO x SVR Hypovolemic (↓ Intravascular volume): • Hemorrhage, dehydration due
- Differential Diagnosis ... failure, acute MI ... findings based on cause ... reactions, adrenal ... #table #comparison
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
diuretics, Saline infusion ... - ↓ Renin/Aldosterone ... ± Renin/Aldosterone ... only if no clear cause ... Elimination (see Table
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... of lactate as a clinical ... / hypoxemia -> focus ... - shock->treatments ... before beginning treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Management Summary Causes ... Dermatomyositis Clinical ... perfusion → renal ... #Management #causes
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... Kidney stones caused ... Receptor Antagonists (Aldosterone ... Tolvaptan) • Treatment ... #Medications #Table
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
lower risk of renal ... Thermodilution CO/CI ... cardiac output causes ... Tolerance #testing #diagnosis ... #criticalcare #comparison
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... thickening or effusion ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... Muscle atrophy may cause ... • Clear cell renal ... Non-small-cell lung ... positive patients Treatment
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