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diagnosis sle druginduced erythematosus management oncology systemic workup algorithm causes cppd disorders drugs gout hcq hodgkins hydroxychloroquine levels lymphoma measurement
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
probably < 1500ng/mL ... Best indications ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... thiazidic, PPI, ACE ... bDMARDs (rare), Topics ... #sle #comparison ... #table #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... permanent alopecia Differential ... La, anti-Jo-1, SCL ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... family history - Medications ... changes), high MCV ... not required in all ... Causes #Workup #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... Malignancies (eg CML ... , ALL) • Solid ... #NonHodgkins #comparison ... #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Better call hematology ... V617F) and MPNs (MPL ... honestly, this list ... Algorithm #workup #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & MBL ... Evans • ITP • Cl-NH ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... Erythematosus #medications ... #drugs #pharmacology ... #risk #differential ... #diagnosis #rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
with CPPD: OA in atypical ... locations: Wrist, MCP ... Metabolic syndrome • Medications ... #CPPD #Gout #Comparison ... #rheumatology #
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