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diagnosis nephrology causes potassium high induced acb algorithm ammonia burden cognitive deprescribing diuresis diuretics drug druginduced drugs dysgeusia encephalopathy excretion
Anticholinergic Cognitive Burden Scale (ACB Scale) Categorical Scoring: • Possible anticholinergics include those listed with ascore
each selected medication ... medications ... #ACB #Scale #Anticholinergic ... Deprescribing #Medications ... #List #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #differential # ... diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Clenching of fist ... • NSAIDs • ACE ... Medications 2. ... #differential #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Clenching of fist ... • NSAIDs • ACE ... Medications 2. ... #differential #
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
ileal conduit - Medications ... Multiple myeloma, CML ... , AML - Large ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Medications Contributing to Dysgeusia Antimicrobial medicines Macrolides, fluoroquinolones, ampicillin, metronidazole, tetracycline, trimethoprim-sulfamethoxazole, amphotericin B, terbinafine and other antimycotic
Medications Contributing ... Angiotensin-converting enzyme (ACE ... erlotinib, imatinib Anticholinergic ... Drugs #Causes #Differential ... #Diagnosis #Pharmacology
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
1.6, low urine Cl ... 0.7, high urine Cl ... with urine Na/Cl ... Other medications ... #diagnosis #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Anterior circulation: MCA ... Reversible course Differential ... Electrolyte abnormality, Medication
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Inhibitors of Na+K+2Cl ... Hyponatremia • Hypercalcemia ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Drug-Induced Urinary Retention Drug-induced urinary retention is very common and can be caused by many classes of
many classes of medication ... acetylcholine (ACh ... Retention: • Anticholinergic ... Drug #Induced #differential ... #diagnosis #pharmacology
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