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diagnosis nephrology causes hyperkalemia high management pathophysiology acidosis aniongap continuous crrt diuresis diuretics druginduced encephalopathy excretion hyperammonemia indications neurology nongap
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
and decreased metabolism ... ileal conduit - Medications ... Multiple myeloma, CML ... , AML - Large ... Hyperammonemia #Differential
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • NSAIDs • ACE ... • Recent IV potassium ... infusions) - Metabolic ... Medications 2.
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Non-anion Gap Metabolic ... Potassium-sparing ... ACE-Is and ARBs ... Acid loads (ammonium ... #Acidosis #differential
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • NSAIDs • ACE ... • Recent IV potassium ... infusions) - Metabolic ... Medications 2.
Continuous Renal Replacement Therapy (CRRT) - Overview Types of CRRT • CVVHD - Continuous Veno-Venous hemodialysis -
Continuous Renal ... Therapy (CRRT) - Overview ... correction of metabolic ... 4K, 2K, or 0K (all ... #Continuous #Renal
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... resistance • Metabolic ... Inhibitors of Na+K+2Cl ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Syndrome (PRES) Overview ... Immunosuppressive agents, Renal ... Reversible course Differential ... Electrolyte abnormality, Medication ... Drug toxicity, Metabolic
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