13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... changes), high MCV ... not required in all
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... experience some symptoms ... three peripheral ... than 150,000 per mcL ... These causes could
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... have fever - ACS ... : • Pathophysiology ... diagnosis #management #hematology
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... varied clinical symptoms ... hormone in almost all ... reflex hammer, caused ... #neurology #endocrinology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
bone marrow and peripheral ... age 70 years Symptoms ... Out Secondary Causes ... Myelogenous Leukemia (CML ... #diagnosis #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Neurological symptoms ... the underlying cause ... with AEDs until cause
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... than one after symptom ... the underlying pathophysiology ... diagnosis #management #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... Malignancy (e.g. hematologic ... Mononeuritis Multiplex • Peripheral ... Induced Lupus: • Symptoms ... La, anti-Jo-1, SCL
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
): - Hematologic ... Treat underlying cause ... fluids (200–300 mL ... : - Seen with AML ... (~20 %) and APL