11 results
Dermatofibroma 
 - Skin-colored to brown papule or nodule 
 - Firm, indurated texture 
 -
Male - Dimple sign ... Dermatofibroma #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... : HLH signs and ... Ferritin >500 ng/mL ... management #treatment #hematology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
is a clinical dermatological ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... Fever is the main clinical ... 5000 to 10,000 ng/mL ... Activation #Syndrome #Diagnosis ... #Management #Hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... dorsal part of the MCP ... Inverse Gottron’s sign ... auricular papules Clinical ... #dermatology #diagnosis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
is a useful clinical ... tool for diagnosing ... #PhysicalExam #Video ... #Clinical #Bullae ... #Blister #Dermatology
General Approach to Anemia - Differential Diagnosis Framework
1) Check reticulocyte count to determine if hypo/hyper-proliferative
2) Exclude
- Differential Diagnosis ... haptoglobin) 3) Use MCV ... & clinical context ... #differential #diagnosis ... #hematology #algorithm
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... Clinical Presentation ... • Common Signs ... #HLH #Hemophagocytic ... #Management #Hematology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... shoulders (in a shawl sign ... dorsal part of the MCP ... auricular papules Clinical ... #dermatology