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Treatment Approach to Hodgkin's Lymphoma

By Matthew Ho, MD PhD @MatthewHoMD
With Credit: Dr Sunita Nasta and Dr
Treatment Approach to Hodgkin's ... Lymphoma By ... guidelines #Hodgkins ... #Lymphoma #oncology ... #Hematology #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hodgkin's Lymphoma ... Hodgkin's Lymphoma ... , Hodgkin Lymphomas ... #comparison #oncology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma ... Hodgkin Lymphoma ... classical HL (MCHL ... Immunohistochemical studies (to differentiate ... #oncology #management
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Biopsy • Non-Hodgkin's ... Biopsy • Hodgkin's ... Lymphoma #Diffuse ... Algorithm #Causes #Hematology ... #Oncology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - Differential ... (Hodgkin) • Elevated ... - Leukemia/Lymphoma ... : NHL, CML • Miscellaneous ... Algorithm #causes #endocrinology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemopathies+++: Hodgkin ... , T-cell lymphoma ... , B-cell lymphoma ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
aseptic meningitis), MCC ... Behcet disease) Differential ... Ischemia, Leukemia, Lymphoma ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... cyclophosphamide) • Hodgkin ... lymphoma and leukemia