10 results
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Lactic Acidosis ... A Lactic Acidosis ... delivery: Hypoxemia, Anemia ... Type B Lactic Acidosis ... Pancreatitis, Renal
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Approach to Acid Base Disorders ... Evaluation and Differential ... : Lactic Acidosis ... #Evaluation #workup ... #Differential #
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Lymphoproliferative Disorders ... Myeloid Leukemia (CML ... - Hemolytic Anemia ... • Diabetic acidosis ... Diagnosis #Algorithm #endocrinology
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... - Differential Diagnosis ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... #Acidosis #Differential
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
(NAGMA) - Differential ... Framework and Workup ... (GFR 20-50 ml/min ... Metabolic #NAGMA #Differential ... #Diagnosis #Workup
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... A Lactic Acidosis ... 30mmHg) - Severe anemia ... B Lactic Acidosis ... #Differential #
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... Differentials? ... (AG) = {Na - (Cl ... failure (uremia ... #AcidBase #disorders
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... Neutropenia • Platelet Disorders ... Workup: • Complete ... blood count with differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Kikuchi disease • Type-I ... APLA/LAC: • Renal ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Connective tissue disorders ... Thalassemia, Sickle cell anemia ... Comment on type ... Gap #ProteinGap #differential