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diabetes diagnosis dm2 management medications pathophysiology acromegaly algorithm causes comparison disorders dosing dpp4 druginduced gout hematology hyperkalemia hyperuricemia inpatient ketones
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors ... - Pharmacology ... Contraindications: eGFR < 30 mL ... #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... These work by inhibiting ... #Inhibitors #Pharmacology ... DM2 #Diabetes #Endocrinology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... • Calcineurin Inhibitors ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology
Diabetes Mellitus Type 2 Inpatient Medication Guide Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP-4 inhibitor ... receptor agonist, SGLT2i ... α-glucosidase inhibitor ... #Medications #pharmacology ... comparison #table #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... Stimulates Insulin, Inhibits ... work by increasing ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
Hyperuricemia - Differential Diagnosis Algorithm Primary - Over-production • Increased turnover of nucleotides Primary
Hyperuricemia - Differential ... Myeloid Leukemia (CML ... drugs • ACE inhibitors ... Hyperuricemia #Differential ... Diagnosis #Algorithm #endocrinology
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
variant seen with SGLT ... inhibitors & pregnancy ... Disorders #ketones #differential ... diagnosis #management #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
Otherwise, it works ... when compared to SGLT2 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Differential Diagnosis ... Diagnosis and Workup ... levels to <1ng/mL ... Diagnosis #Management #Endocrinology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myelogenous Leukemia (CML ... Workup: • Complete ... blood count with differential ... methyltransferase inhibitors
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