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management dermatology oncology photo cutaneous dermatomyositis differential disease erythematosus lupus sle stills systemic activation adult adultonset antimda5 antimda5dm antinxp2 antinxp2dm
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... Complications: MAS ... management #treatment #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... ) Blood (75%): Anemia ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... Differential Diagnosis ... #rash #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... Headaches • Pale skin ... #oncology #hematology ... #diagnosis #management
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... maculopapular skin ... Ferritin >3000 ng/mL ... Gf consider MAS ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
. diagnosis? ... self-limited Diagnosis ... is clinical & labs ... larva #migrans #skinRash ... #dermatology #clinical
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... #Rheumatology
Capnocytophaga Canimorsus Skin Rash 40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... possible Patient's clinical ... the key to the diagnosis ... #Rash #dermatology ... #clinical #photo
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