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diagnosis management differential leukemia chronic classification disorders hodgkins lymphocytic workup blood cancer cell comparison diffuse dlbcl erythematosus hemeonc hemophagocytic hlh
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm By Matthew Ho, MD PhD @MatthewHoMD #Diffuse
Diffuse large B cell ... lymphoma (DLBCL ... Algorithm By ... #Algorithm #oncology ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Involvement - B-cell ... CD10 - T-cell ... Cells - B-cell ... CD23, o CML ... Blood #Disorders #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... is of B-cell lineage ... marrow • Mature B-cell ... involvement • T-cell ... #Hematology #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... Reed Sternberg cell ... type (B cell, T ... Malignancies (eg CML ... #differential #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
and other C Cell ... microglobulin Treatment ... • Mantle cell ... diagnosis #workup #oncology ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... common - T Cell ... ~10% - B-Cell ... Responsive to Treatment ... pathophysiology #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Transformation to large cell ... lymphoma (Richter ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
++: Hodgkin, T-cell ... lymphoma, B-cell ... lymphoma (DLBCL ... Unknown cause Treatment ... #summary #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... classical HL (MCHL ... Treatment • Early ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... hematopoiesis cell ... Myelogenous Leukemia (CML ... Syndromes #diagnosis #hematology ... #oncology
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