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diagnosis management associations antibodies classification comparison differential disease diseases druginduced hodgkins igg4 lupus lymphoma mds monoclonal myelodysplasia myelodysplastic paraproteinemias phenotypes
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... Polymerase Ill • ANCA Vasculitis ... #Rheumatology # ... #associations #table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... syndrome Anti-Scl ... disease c-ANCA - Vasculitis ... diseases #diagnosis #table ... #rheumatology #
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
with response to treatment ... serum lgE, no autoantibodies ... No necrosis, No vasculitis ... management #phenotypes #workup ... #treatment #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... ) Autoantibodies ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months) and of autoantibodies ... • Immunologic Workup ... sle #comparison #table ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
classical HL (MCHL ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myelogenous Leukemia (CML ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
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