14 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... extramedullary disease ... • Tumor lysis syndrome ... -> Invade Skin: ... #Hematology #Oncology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
• Eosinophilic Leukemia ... GI, lung, skin), ... Heme malig (AML, CML ... , Behcet disease ... , Sarcoidosis, SLE
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Hepatomegaly • Skin ... cells can indicate disease ... diagnosis #workup #oncology ... #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Oral aphthae : SLE ... tears, Ischemia, Leukemia ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... general feeling of ill ... , breast CA - Hematologic ... - Allergic contact ... #oncology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
arthritis - SLE ... - Behcet Disease ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... - Leukemia
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... La, anti-Jo-1, SCL ... Hodgkin lymphoma and leukemia
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Pathergy Summary Overview

What is pathergy?
Pathergy is an exaggerated skin injury occurring after minor trauma such as
following: • Behcet ... Disease • Pyoderma ... Chronic myeloid leukemia ... (CML) treated with ... #differential #allergy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... (CML) • Felty ... Cell Leukemia ... Myeloproliferative Disease ... #oncology