18 results
diagnosis rheumatology differential dermatology erythematosus hemophagocytic leukemia lupus lymphohistiocytosis myelodysplastic summary systemic treatment vasculitis activation allergy behcet chronic clinical cll
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
most frequent skin ... appearing during the disease ... dermatomyositis, SLE ... #oncology #clinical ... #skin
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... erythematosus [SLE ... • HLH Labs: ... #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology ... #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... Oral aphthae : SLE ... • Arthritis: SLE ... #diagnosis #management ... signs #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... Ferritin >500 ng/mL ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... La, anti-Jo-1, SCL
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... • Autoimmune diseases ... : - 10% SLE or ... diagnosis #types #classification ... #rheumatology #
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... (MCHL) - Lymphocyte ... number of sites of disease ... #hematology #oncology ... #management
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