10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Treatment: • Inflammatory ... cerebritis #diagnosis #management
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Guillain-Barré syndrome ... GBS), systemic lupus ... IU/I • SAMS clinical ... myopathy #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
release of pro-inflammatory ... disease • Systemic lupus ... SJIA], systemic lupus ... 5000 to 10,000 ng/mL ... #Diagnosis #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Disease (25-75%): Inflammatory ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... photosensitivity, inflammatory ... Clinical Features ... : • Symptoms limited ... La, anti-Jo-1, SCL
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... renal failure Clinical ... skin (16-32%): lupus ... Sarcoidosis #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... Etiology: • Pathophysiology ... Neurological symptoms ... Anterior circulation: MCA ... #diagnosis #management
KSHV Inflammatory Cytokine Syndrome (KICS)
Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
KSHV Inflammatory ... Cytokine Syndrome ... 3, and 4. 1) Clinical ... Symptoms: Fatigue ... Kaposi #diagnosis #management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
of idiopathic MCD ... including systemic lupus ... cell lymphoma Pathophysiology ... and the systemic symptoms ... TAFRO #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Clinical Presentation ... Common Signs and Symptoms ... Pathophysiology ... Overproduction of pro-inflammatory