25 results
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. 

#pharmacology
Summary table of ... #pharmacology #dm2 ... medications #overview #management
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... agent • Does not cause ... #Metformin #Pharmacology ... #Summary #DM2 #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Summary Mechanisms ... Ozempic), or daily tablet ... not definitively cause ... #Summary #DM2 #
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Summary Mechanisms ... Contraindications: eGFR < 30 mL ... hypovolemia) • GU infections ... #Summary #DM2 #
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Summary Mechanisms ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 #
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Summary Vasopressors ... • Higher doses cause ... cAMP/cGMP • Causes ... #Summary #management
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Resistance, Main Uses ... Vasopressors #Properties #Table ... #Pharmacology # ... Effect #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
sIL-2R >2400 Ul/ml ... Drugs, Unknown cause ... Etoposide/VP16 (100 mg/m2 ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary
IDSA Recommendations for Preventing and Treating Penicillium marneffei Infections in HIV-AIDS
Preventing 1st Episode of Penicilliosis (Primary
Penicillium marneffei Infections ... 100 cells/mm3 g/mL ... Treating Acute Infection ... Prevention #Treatment #management ... #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Bacterial Enteric Infections in HIV-AIDS
Preventing Bacterial Enteric Illness:
 • Antimicrobial
Bacterial Enteric Infections ... • In rare cases ... if MIC<0.12 ug/ml ... Prevention #Treatment #management ... #HIVAIDS #pharmacology