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diagnosis causes hematology hyperkalemia high nephrology algorithm druginduced drugs erythematosus hypomagnesemia hypomg leukemia lupus oncology pathophysiology platelets secondary sle systemic
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Myelodysplastic syndrome ... myeloid leukemia (CML ... #Differential # ... Diagnosis #Causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... #Platelets #Differential
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Hemolysis, thrombocytosis ... • Recent IV potassium ... - Tumor lysis syndrome ... Medications 2.
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • Hemolysis, thrombocytosis ... • Recent IV potassium ... - Tumor lysis syndrome ... Medications 2.
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
osmotic diuresis - Potassium ... disorders: - Syndrome ... Causes #diagnosis #differential ... #medications #drugs ... #pharmacology #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
basophilia, and thrombocytosis ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Intracellular Urate, Potassium ... #Leukemia #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
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