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diagnosis nephrology algorithm causes treatment metabolic gitelman potassium hematology pharmacology cardiology chloride criticalcare foamed low medications neurology oncology rhabdomyolysis summary
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Normotensive: • UCl ... Post-hypercapnia • UCl ... #Hypokalemia # ... Differential #Diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... - Differential ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... - Differential ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... - Differential ... K-ATPase which imports ... - Refeeding Syndrome ... potassium #low #pathophysiology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
- Differential ... Urinary Chloride • Cl ... Kidney loss of Cl ... - Loss of Cl ... Cystic fibrosis) • Cl
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... #differential # ... diagnosis #pathophysiology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #Pathophysiology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... • Low Urine Cl ... • High Urine Cl ... #hypokalemia ... urine #potassium #differential
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Chloride Algorithm Cl ... Kidney loss of Cl ... • Loss of Cl- ... Cystic fibrosis Cl ... Algorithm #nephrology #differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Hypochloremic metabolic alkalosis ... Hypocalciuria (spot ... ratio 0.5%) Differential ... diagnosis #nephrology #management ... #pathophysiology
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