18 results
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... transformation (CML ... hyperleukocytosis (AML ... #Causes #Differential ... #Management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... (AG) = {Na - (Cl ... D D-lactate (short ... bowel syndrome, ... Base #Gas #VBG #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Pathophysiology ... initiation • Differential ... APML #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... complete paralysis of all ... • Weakness: Starts ... #diagnosis #management ... #treatment #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
aseptic meningitis), MCC ... Behcet disease) Differential ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... Myelogenous Leukemia (CML ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... disequilibrium syndrome ... irrigation • Management ... Inhibitors of Na+K+2Cl ... Tolvaptan) • Treatment
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Differential Diagnosis ... Beckwith Wiedemann syndrome ... levels to <1ng/mL ... Endocrinology #Treatment ... #Pathophysiology