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hematology syndrome treatment apml autoimmune causes classification crisis differentiation erythematosus fungal hemolytic hodgkins hospitalization infections infectiousdiseases lupus lymphoma mds monoclonal
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... 1) DIAGNOSE AIHA ... • Blood smear: Differential ... #diagnosis #management ... #treatment #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... Diagnosis: Infection ... #management #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & MBL ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... classical HL (MCHL ... Immunohistochemical studies (to differentiate ... #oncology #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and Management ... and pernicious anemia ... Person Syndrome Pathophysiology ... levels of GAD, an antibody ... #Management #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... Myelogenous Leukemia (CML ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... to around 500 mL ... of unnecessary diagnostic ... #differential # ... diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... La, anti-Jo-1, SCL ... #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... Inhalation of spores ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... #Management #Infections
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... Initiate ACEi (short-acting ... Renal #Crisis #rheumatology ... #management
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