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management antibiotics infant pediatrics rheumatology risk stepbystep stratification classification disease em hemophagocytic hlh lymphohistiocytosis oncology stills adult adultonset aosd apml
Validation of the Step-By-Step Approach to Febrile Infants #Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Infants #Diagnosis ... Management #Pediatrics #Peds ... #StepByStep #Algorithm ... #LP #Antibiotics ... Stratification #Fever
Algorithm for the differentiation between simple and complex febrile seizures. Guidelines for evaluation of each. #Diagnosis
Algorithm for the ... #Diagnosis #Management ... #EM #Neuro #Peds ... #Fever #Seizure ... #Algorithm #Workup
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #Febrile #Infant ... #LP #Antibiotics
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
uncharacterized fevers ... with LP Meningitis ... particularly complex febrile ... #Peds #EM #Classification ... #Fever #SBI #SeriousBacterialIllness
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... #EBM #Management ... #Pediatrics #Peds ... #LP #Antibiotics ... Stratification #Fever
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Coxsackie, CMV, EBV ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
acute or subacute febrile ... following: • Fever ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... Imaging: CXR- pulmonary ... #management #hematology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
extremities during febrile ... Ferritin >3000 ng/mL ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... sIL-2R >2400 Ul/ml ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
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