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management rheumatology risk antibiotics febrile infant lp oncology pediatrics stepbystep activation apml calcium cancer cppd deposition differentiation disease ebm emergencies
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... Antibiotics #Risk #Stratification ... #Fever
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
- Nonremitting fever ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... #hematology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... Management #Pediatrics #Peds ... Antibiotics #Risk #Stratification ... #Fever
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
: - Fever + ANC ... ): - Hematologic ... fluids (200–300 mL ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
or family - Ever ... murmur 3/6) - Pulmonary ... event, follow ACC algorithm ... Risk #Evaluation #stratification ... #diagnosis
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- Anasarca - Fever ... disease, severe fever ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... agonists #TAFRO #diagnosis
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
current treatment ... algorithm 2018. ... median age at diagnosis ... cardiovascular or pulmonary ... #algorithm #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
locations: Wrist, MCP ... culture used to diagnose ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... acute neck pain, fever
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