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diagnosis management dermatology lupus oncology sle syndrome systemic dermatomyositis hemophagocytic hlh lymphohistiocytosis signs summary symptoms activation antimda5 antimda5dm antinxp2 antinxp2dm
Janeway Lesion: Flat, painless, erythematous lesions seen on the palm of this patient's hand. While frequently associated
Flat, painless, erythematous ... endocarditis, in this case ... Photo credit, Josh ... Images #Clinical ... #Photo #Dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Systemic Lupus Erythematosus ... (SLE) Clinical ... autoantibodies that will cause ... #rheumatology #
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... anemia (MCV 80- ... than 150,000 per mcL ... well as varying clinical ... These causes could
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... and CNS • Headache ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... and petechiae Causes ... Treatment: ... #oncology #hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... dorsal part of the MCP ... violaceous macules and erythematous ... auricular papules Clinical ... Dermatomyositis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... basal ganglia, CNS ... Behcet syndrome (Clinical ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
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