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differential hematology monoclonal gammopathy management oncology agglutinin anemia bee cold complications disease hemolytic ms multiple myelitis noninflammatory paraproteinemias sclerosis significance
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... Neurologic-Centered ... Renal-centered (ie "MGRS ... #Significance #MGUS
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... • MGCS • MGRS ... et diutinum Neurologic ... Dermato-neuro syndrome) MGRS ... to cold IgG • Lupus
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS) Fracture, Osteoporosis - Increased osteoclast activity and bone resorption
Significance (MGUS ... treatment of infective symptoms ... rituximab (in clinical ... high-risk situations #MGUS ... Complications #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... (Cold-induced symptoms ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
resonance imaging [MRI ... patients with clinically ... stimulation Clinical ... objective evidence of neurologic ... #management #neurology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
conjunction with symptoms ... neuropathy (LHON) plus MRI ... lesions and clinical ... consistent with MS ... BEE #Syndromes #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... Transverse Myelitis Diagnosis ... #management #neurology
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