43 results
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... Light-Chain MGUS
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
marrow plasma cell ... focal lesions on MRI ... diseases, CML, ... #Gammopathies #MGUS ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... with no early symptoms ... Diagnosis: • ... microglobulin Treatment
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology ... #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... immunophenotype Clinical ... uw_IMresidency #CLL ... #hemeonc #diagnosis
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... antibody - Early treatment ... of infective symptoms ... rituximab (in clinical ... high-risk situations #MGUS
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... - **MSK rads ... • PVNS/Giant Cell ... #diagnosis #msk ... #rheumatology
Krabbe Disease 

Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Diagnosis was made ... testing and expedite treatment ... neurotoxic • Symptoms ... Krabbe #Disease #Diagnosis ... #MRI #Clinical
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... and duration of symptoms ... angioedema Other symptoms ... Atopic diseases, Chronic ... #rheumatology #
Osgood-Schlatter Disease - MSK Radiology
Imaging Findings:
 • Infrapatellar fat-pad edema with loss of the patellar tendon
Osgood-Schlatter Disease - MSK ... DOES NOT OSD in all ... tear (similar symptoms ... #mri #clinical ... #msk