16 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... Renal-centered (ie "MGRS ... #Significance #MGUS ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... constitutional symptoms ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
focal lesions on MRI ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... antibody - Early treatment ... of infective symptoms ... rituximab (in clinical ... high-risk situations #MGUS
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... (Cold-induced symptoms ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... caucasian • Symptoms ... R-G or B-Y • MRI ... - Typical MS-like ... #rheumatology #
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
resonance imaging [MRI ... patients with clinically ... stimulation Clinical ... Multiple Sclerosis Treatment ... management #neurology #treatment
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
conjunction with symptoms ... and treatment can ... neuropathy (LHON) plus MRI ... lesions and clinical ... consistent with MS
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... microglobulin Treatment ... #workup #oncology ... #hematology