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diagnosis hyperkalemia nephrology pharmacology causes agitation algorithm binder bipolar bpd criticalcare delirium disorder druginduced icu kbinder lithium management medications pad
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
renal failure • Drugs ... Increased potassium ... Normal, Renin High ... hypoplasia Aldosterone high ... #differential
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
g once daily Increase ... from other oral drugs ... this from other drugs ... after) to avoid interactions ... #Hyperkalemia #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Cyclosporine) • Increased ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... reactions Common Drugs ... hypoperfusion Increased ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... reactions Common Drugs ... hypoperfusion Increased ... #high #nephrology
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
Hydromorphone (Dilaudid) - Increased ... A dissociative drug ... metabolism (med interactions ... No pharmacologic ... (Haldol) - No pharmacologic
Lithium Therapy for Bipolar Disorder Toxicity Levels: - Mild (1-1.5 mEq/L) - Moderate (1.6-2.5
diuretics all increase ... If levels are high ... Common drug interactions ... include these drugs ... BPD #Toxicity #Pharmacology
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