12 results
ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
ANTIBIOTIC SUSCEPTIBILITIES ... with new bugs & drugs ... Susceptibilities #ICU ... CriticalCare #Overview ... #Pharmacology #
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview

Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis
Spectrum: covers MRSA
Class Overview ... arthralgias and lots of drug-drug ... interactions (CYP450 ... #Pharmacology #Antibiotics ... #Review #Overview
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat 

Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
boosters used in HIV treatment ... metabolism of drugs ... both have lots of drug ... interactions because ... HIV #Boosters #Pharmacology
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Echinocandins - Antibiotics ... Class Overview ... vs Candida -> Drug ... But higher MICs ... Anidulafungin #Pharmacology
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
antirheumatic drug ... prophylaxis and treatment ... interactions, including ... beta blockers (increased ... Hydroxychloroquine #HCQ #Pharmacology
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
INDICATION: Treatment ... g once daily Increase ... from other oral drugs ... after) to avoid interactions ... #Hyperkalemia #Pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia - Overview ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... - β-lactam antibiotics ... aplastic anemia Treatment
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Hydromorphone (Dilaudid) - Increased ... A dissociative drug ... metabolism (med interactions ... No pharmacologic ... (Haldol) - No pharmacologic
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview ... including PCP PNA (drug ... choice, both for treatment ... #Pharmacology #Antibiotics
Lithium Therapy for Bipolar Disorder 
Toxicity Levels: 
 - Mild (1-1.5 mEq/L) 
 - Moderate (1.6-2.5
diuretics all increase ... maintenance agent for treatment ... Common drug interactions ... include these drugs ... BPD #Toxicity #Pharmacology