19 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... sign is not useful ... #Meningitis #Clinical ... #PhysicalExam #Pediatrics
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Paradoxical Breathing on Physical Exam

Paradoxical breathing is often a sign of breathing problems. It causes the
often a sign of ... It causes the chest ... #respiratory #clinical ... #video #pulmonary ... #peds #pediatrics
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TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 2 hit mechanism ... without other cause ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
accounts for —9096 of cases ... Pathophysiology ... onset widespread pulmonary ... FES is a clinical ... Syndrome #Diagnosis #Signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... Diagnosis: - MRI is
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
arteritis (GCA) 1) Is ... visual loss caused ... Clinical manifestations ... Doppler US : halo sign ... Ophthalmology #Diagnosis #Algorithm
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds #pediatrics
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... : • Process is ... organ damage Clinical ... Treat primary cause ... treatment #management #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
thrombophlebitis, pulmonary ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... • TTP, HUS and HIT ... #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
93-95% Pathophysiology ... renal failure Clinical ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... Diagnosis #Management #Signs