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diagnosis hhv8 management castleman comparison differential disease kaposi kshv algorithm castlemans classification cytokine dementia diseases druginduced geriatrics hivaids humanherpesvirus idsa
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
neurocognitive disorders (MNCD ... workup What type of MNCD ... TerrierBen #MNCD
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Membranous GN, MCD
HHV8/KSHV-reIated diseases: From Cellular Proliferation to Hyperinflammation Kaposi sarcoma (KS): • Target organs: Ubiquitous (cutaneous and mucosal
Castleman Disease (MCD
CASTLEMAN DISEASE Disorder of the immune system with excessive production of IL-6 Castleman’s disease is a rare, heterogeneous
Castleman disease (MCD ... are common in MCD ... a hallmark of MCD ... proportion of MCD ... can be seen in MCD
Unicentric Castleman Disease (UCD) vs Multicentric Castleman Disease (MCD) - Comparison Table Unicentric Castleman Disease (UCD): •
Castleman Disease (MCD ... Castleman Disease (MCD ... HHV-8-associated MCD
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
of idiopathic MCD ... Idiopathic MCD without ... mimics that of MCD
KSHV Inflammatory Cytokine Syndrome (KICS) Working Case Definition for KICS: Requires at least 2 clinical manifestations (from
- Exclusion of MCD
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
Castleman’s Disease (MCD
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