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diagnosis nephrology differential algorithm aki causes management renal acute disease injury pharmacology pathophysiology chronic classification clinical glomerulonephritis nephro ebm nejm
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
Definitions of AKI, CKD ... , AKD Acute Kidney ... Oliguria Chronic Kidney ... > 3 months • Kidney ... months Acute Kidney
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
HTN, Vasculitis Glomerular ... , Amyloidosis, MPGN ... • Nephritic: RPGN ... , IgA, Alport, MPGN
Kidney Biopsy - Diagnosis Algorithms 1) Normal Glomerulus by LM 2) Glomerular Crescents 3) Double Contours of GBM 4) Endocapillary
Kidney Biopsy - ... Algorithms 1) Normal Glomerulus ... by LM 2) Glomerular ... Hypercellularity #Kidney
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN ... formation along glomerular ... Complement-Mediated MGPN ... , CFHR5 neph) MPGN ... Glomerulonephritis #MPGN
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Glomerulonephritis (RPGN ... ) - Loss of kidney ... with evidence of glomerular ... immune deposits in glomeruli ... Glomerulonephritis #RPGN
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
Clock for Staging CKD ... Staging CKD is ... the estimated glomerular ... as a proxy for kidney ... filtered in the kidney
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
metformin in T2D and CKD ... . chronic kidney ... eGFR. estimated glomerular ... , #KDIGO2020 #CKD ... Management in CKD
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD EMPA-REG OUTCOME - Empagliflozin lowered CV events
and CKD EMPA-REG ... SGLT2i in HF and CKD ... lowered adverse kidney ... lowered adverse kidney ... #CKD
Causes of Hematuria - Glomerular vs Non-glomerular == Glomerular == - Glomerulonephritis - Thin basement membrane disease ==
of Hematuria - Glomerular ... vs Non-glomerular ... == Glomerular ... == Kidney - ... - Polycystic kidney
NSAID vs ACEI/ARB effects on the Kidneys Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
effects on the Kidneys ... effects on the kidneys ... contribute to kidney ... patients have CKD ... used for their kidney
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