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Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
C-ANCA): GPA >>> MPA ... > eGPA • MPO-ANCA ... P-ANCA): eGPA, MPA ... Glomerulonephritis #Vasculitis #differential
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (MPA ... associated with MPO ... polyangiitis - MPO ... polyangiitis - MPO ... #CANCA #PANCA #MPO
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis MPA → usually p-ANCA GPA → usually c-ANCA EGPA →
Auto-antibodies and Differential ... Diagnosis MPA ... 50% P-ANCA (MPO ... Vasculitis #AAV #Differential
ABCs of Lung Ultrasound - POCUS Pitt Internal Medicine Point of Care Ultrasound @PittIMPOCUS .mp4 Hi-Res Version Here:
PittIMPOCUS .mp4 ... profiles-ultrasound-differential-pocus-lung
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 Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA ... Induction: GC+MTX ... #Polyangiitis #MPA
Prolonged neuromuscular blockade - Differential Diagnosis - Drugs, Acid-base Disorders, Metabolic, Neurologic, Electrolyte abnormalities By Mark Harris, MD
neuromuscular blockade - Differential ... Mark Harris, MD MPH ... blockade #Prolonged #Differential
Hypoxemia in Anesthesiology - Differential Diagnosis and Management Management: • increase Fi02 to 100% - verify!
Anesthesiology - Differential ... Mark Harris, MD MPH ... Anesthesiology #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... present in >90%, MPO ... Granulomas - MPO ... ear disease Differential ... #Vasculitides #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
polyangiitis - MPO ... PR3 (80-90%) > MPO ... involvement - PR3>MPO ... Churg-Strauss) - MPO ... Anti-GBM disease - MPO
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
Mesenteric Ischemia - Differential ... , [E]GPA, IgA, MPA ... Ischemia #Schema #Differential
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