16 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... Drug-associated, PCH, Evans Syndrome ... Laboratory Tests ... #Diagnosis #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... - DRESS - AIN ... (vasculitis / autoimmune ... Hypereosinophilic Syndrome ... Diagnosis #Causes #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... Rheumatologic Disease ... #Differential # ... Diagnosis #MSK # ... rheumatology #Monoarticular
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... improves quickly with rest ... e.g., meniscal tears ... #MSK #rheumatology ... approach #workup #differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
is a skin prick test ... Behcet disease) Differential ... Giant retinal tears ... Nonsurgical abdominal pain ... signs #symptoms #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... chills, flank pain ... • Diagnostic Test ... hemolytic #anemia #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... lesions • Severe pain ... Palpable Rash: - Autoimmune ... Fecal occult blood test ... • Abdominal ultrasound
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Inflammation of ear ... conditions #joint #pain ... #differential # ... diagnosis #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Symptomatic: artificial tears ... #Rheumatology #