20 results
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
... laboratory tests ... MRI, iADL scale, ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Frontal atrophy Vascular
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... activity of factor X, vascular ... Protein • AL Amyloid ... enlargement • MRI
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
• Myopathy (Also ... caused by hydroxychloroquine ... Erythematosus #SLE #MSK ... #signs #symptoms ... #diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... 4) progressive muscular ... Escorial criteria uses ... MRI: Brain, cervical
Medial Meniscus Bucket Handle Tear - MSK Radiology
Imaging Findings:
 • Truncation of the medial meniscus on
Handle Tear - MSK ... The "double PCL sign ... displaced fragment is also ... red zone of the vascular ... BucketHandle #Tear #knee #mri
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... Hypercortisolism - Diagnosis ... , oral cavity) Caused ... dexamethasone suppression test ... #signs #symptoms
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Generalized fatigue - ALS ... Bedside: ice pack test ... /Edrophonium test ... - Cogan sign ... - Peek sign 2.
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... symptoms are not caused ... mediators such as ... anterior/posterior MSK ... #Management #Signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... • Bilateral signs ... Transverse Myelitis Diagnosis ... negative, MOG-IgG test