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neurology management rheumatology caudaequina classification endocrinology symptoms vasculitis acromegaly als amyloidosis amyotrophic autoimmune buckethandle cauda clinical comatose cushings dementia encephalopathy
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
... laboratory tests ... MRI, iADL scale, ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Frontal atrophy Vascular
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
: • Nephrotic syndrome ... Carpal tunnel syndrome ... activity of factor X, vascular ... hypoadrenalism • Nausea ... enlargement • MRI
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... Inflammatory: Myeloma/amyloid ... Lack of UMN/LMN signs ... EMG) studies • MRI
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Diagnosis: • ... lumbar stenosis • Vascular ... Imaging studies: • MRI ... #differential # ... diagnosis #causes
Medial Meniscus Bucket Handle Tear - MSK Radiology Imaging Findings: • Truncation of the medial meniscus on
Handle Tear - MSK ... The "double PCL sign ... red zone of the vascular ... Differential diagnosis ... BucketHandle #Tear #knee #mri
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Bilateral signs ... negative, MOG-IgG test ... • Infectious causes ... management #neurology #differential
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Bedside: ice pack test ... /Edrophonium test ... - Cogan sign ... - Peek sign 2.
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Hypercortisolism - Diagnosis ... , oral cavity) Caused ... dexamethasone suppression test ... #signs #symptoms
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... cortical lesions • Vascular ... narrowing on MRA ... Reversible course Differential ... the underlying cause
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