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• Dietary
Deficiency
... • Pancreatic
Disease
... B12 and Folate
Deficiency
... • Liver
Disease
... Macrocytic #Anemia #
Macrocytosis
If persistent
macrocytosis
... restricted diet/
deficiency
... fatigue despite
disease
B12 (Cobalamin)
Deficiency
... to IBD, celiac
disease
... hypersegmented neutrophils,
macrocytosis
... B12 #Cobalamin #
Deficiency
B12 and Folate
Deficiency
... VitaminB12 #Folate #
Deficiency
... FolicAcid #Diagnosis #
Macrocytosis
patients with
macrocytosis
... if vitamin B12
deficiency
... occur with B12
deficiency
... #Diagnosis #
Macrocytosis
RBC: Pyridoxine
deficiency
... Thalassemia, Iron
deficiency
... B12 or Folate
deficiency
... Cell RBC: G6PD
deficiency
... elliptocytosis, Severe iron
deficiency
Consider sickle cell
disease
... ' nucleotidase
deficiency
... , Hexokinase
deficiency
... Cold agglutinins
disease
... , Hemoglobin H
disease
reaction - Atopic
disease
... lymphomas, Hodgkin
disease
... , IgG4-related
disease
... inflammatory bowel
diseases
... malignancy - Immune
deficiency
Malabsorption: • Lactase
Deficiency
... Fibrosis • Celiac
Disease
... Primary Immuno-
Deficiency
... Dissacharidase
Deficiency
... Inflammatory Bowel
Disease
80 fL) • Iron
Deficiency
... Anemia of Chronic
Disease
... Renal
Disease
, Liver ... 100 fL) • B12
Deficiency
... • Folate
Deficiency
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