13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Treatment: • Inflammatory ... Pathway - Lupus Cerebritis ... Erythematosus #SLE #CNS #neurology ... #diagnosis #management
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory ... Syndrome in Children ... disease • Positive COVID ... MISC #Kawasaki #Comparison ... #Syndrome #Children
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
CIDP, chronic inflammatory ... GBS, Guillain-Barré ... syndrome; HNPP, ... #Diagnosis #Neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... like illnesses, COVID ... #Syndrome #diagnosis ... #management #treatment ... #neurology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory ... Antisynthetase Syndrome ... TerrierBen #Inflammatory ... Idiopathic #Myopathy #Comparison ... #Managment #algorithm
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
disease, Leprosy • Inflammatory ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... diagnosis #causes #neurology
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
pneumonia • COVID ... reconstitution inflammatory ... syndrome (IRIS) ... • Ramsay Hunt syndrome ... Indications #infections #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Cytomegalovirus, Epstein-Barr ... GBS #Guillain #Barre ... #Syndrome #diagnosis ... #management #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
myopathy, Guillain-Barré ... syndrome (GBS), ... antisynthetase syndrome ... Statins → Inflammatory ... myopathy #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... and M panel Management ... : • Nephrotic syndrome ... infections (Epstein-Barr ... syndrome, HIV)