495 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Diagnosis #Management
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... suspect underlying hematologic ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Causes of Erythema ... Mnemonic NO cause ... Sarcoidosis or Lofgren's syndrome ... Nodosum #Mnemonic #Causes ... Differential #Diagnosis #Dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Non malignant hematologic ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Hyperthermia Syndromes Comparison
Serotonin Syndrome - NMS - Malignant Hyperthermia - Malignant Catatonia
Cause - Onset - Vitals
Hyperthermia Syndromes ... Comparison Serotonin Syndrome ... Malignant Catatonia Cause ... Mental Status - Treatment ... #Hyperthermia #Syndromes
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... #Causes #Differential ... #Diagnosis #Treatment ... #Management
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Hepatopulmonary Syndrome ... • Hepatorenal Syndrom ... Complications #diagnosis #management ... #summary #hepatology