423 results
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... edema, compartment syndrome ... filling +++ (risk of pulmonary ... of infections) ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... confirm DAH, r/o infection ... differential #diagnosis #management ... #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... APML #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
IDSA Aspergillosis Treatment
 • Invasive pulmonary aspergillosis (IPA)
 • CNS aspergillosis
 • Cardiac Aspergillus infection
 •
Aspergillosis Treatment ... • Invasive pulmonary ... of eye Infectious ... Aspergillosis #Treatment ... #management #pharmacology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... respiratory distress syndrome ... failure - Infectious ... macrophages Treatment ... #diagnosis #management
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
Summary of Infections ... play a role in treatment ... reconstitution inflammatory syndrome ... • Ramsay Hunt syndrome ... #management #treatment
Strongyloides Stercoralis
EPIDEMIOLOGY - ASSOCIATED WITH SOUTHEASTERN U.S.:
 • 0-6% US Prevalence of those:
 • ~30% Asymptomatic
- Migration to Pulmonary ... • IgG ELISA TREATMENT ... several weeks after infection ... HYPERINFECTION SYNDROME ... Stercoralis #diagnosis #management
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... Myositis MIMICS: - Infections ... : Hantavirus infection ... Disseminated S. aureus infection ... Kumfer @AnnKumfer #Pulmonary
Initiation of ART in HIV patients with Opportunistic Infections
 • Pulmonary TB and CD4 cell count
Opportunistic Infections ... • Pulmonary TB ... count <50 • Pulmonary ... of starting OI treatment ... #management #infectiousdiseases