9 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cause Organ Damage ... Labs/Diagnosis: ... lupus erythematosus
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... Clotting factor deficiency ... (lupus, RA, Sjogren's ... immunoglobulins & cryoglobulins
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Diagnosis Framework ... Disease: Discoid lupus ... , Loose anagen syndrome ... Vitamin D levels Systemic ... #dermatology #Hairloss
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... mucositis - Rash ... lupus erythematosus ... Symptoms (Sx) in ... Serologies for Cryoglobulins
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... and permanent alopecia ... disease • Prolidase deficiency ... : • Symptoms limited ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... , mucositis • Rash ... • Progressive symptoms ... tract, and often causes ... #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... malignancies, vasculitis ... processes: • Systemic ... Skin necrosis • Purpura ... • Negative causes
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... Leukocytoclastic vasculitis ... - Lupus - Leukemia ... #diagnosis #dermatology