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rheumatology dermatology algorithm erythematosus classification diffuse vasculitis activation bruising comparison druginduced extravascular focal hair hemolysis hemolytic high hyperkalemia intravascular loss
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diagnosis Algorithm ... • Loose anagen syndrome ... Diffuse #Focal #HairLoss ... #Alopecia #dermatology ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Allopecia - Differential ... , Loose anagen syndrome ... Vitamin D levels Systemic ... Diagnosis #dermatology ... #Hairloss
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Manifestations: Malar rash ... Photosensitivity, Alopecia ... #lupus #Systemic
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... , Vasculitis, Purpura ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #SLE #systemic
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Irreversible-biopsy required • Lupus ... • Loose anagen syndrome ... stress #Diffuse #HairLoss ... #Alopecia #dermatology ... #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... necrosis) • VIT K deficiency ... Diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential ... disease • Prolidase deficiency ... lymphopenia, low PLT • Anemia ... #Systemic #Lupus
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic purpura ... usually IgG) (e.g. lupus ... G6PD deficiency) ... #differential # ... diagnosis #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... • Nephrotic syndrome ... #Differential # ... Diagnosis #Algorithm ... #causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... months to years) Systemic ... Photosensitivity, Alopecia ... #table #rheumatology ... #diagnosis #management
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