8 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Diagnosis Algorithm ... (lupus, RA, Sjogren's ... cryoglobulins • Skin ... #Differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
mucositis - Rash ... : • Behçet Syndrome ... Presentation - Systemic Symptoms ... : strong sign of ... differential #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
M > F Clinical Manifestations ... lesions, palpable purpura ... disease) Differential ... #management #signs ... #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... : Strong sign of ... , mucositis • Rash ... Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... disease • Prolidase deficiency ... : • Symptoms limited
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
and ophthalmic complications ... Manifestations depend ... diagnosis = vasculitis ... required due to skip ... #Symptoms #Diagnosis