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diagnosis hematology cobalamin differential management oncology aplastic causes disease gastroenterology myelodysplasia myelodysplastic nutrition platelets syndromes thrombocytosis
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
B12 Deficiency ... Intestine: SIBO, Celiac ... Stomach: Pernicious anemia ... Gastritis Other: Medications ... #B12 #Deficiency
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
disease • Iron-deficiency ... anemia unresponsive ... to treatment ... Autoimmune • CVID • Medications ... NSAlDs, ARBs) • Infection
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... Vasculitides, IBD, Celiac ... • Reaction to Medications
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... gastric acidity, medications ... related to IBD, celiac ... Check for IF ab Treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... - Antithyroid medications ... Idiopathic • Infections ... Treatment:
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Nutritional: vitamin ... B12 or folic acid ... deficiency • Exposure ... • Parvovirus infection ... • Copper deficiency
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