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differential causes hyponatremia management algorithm comparison gitelman pathophysiology rhabdomyolysis treatment defects drugs epithelial features hypernatremia hyperreflexia hypomagnesemia hypomg hyporeflexia hypotonic
Parkinson Plus Syndromes #Diagnosis #Neurology #Parkinsons #Plus #Syndromes #Comparison #Table #PSP #LewyBodyDementia #Progressive #SupraNuclearPalsy #MSA #MultipleSystemAtrophy
Parkinson Plus Syndromes ... #Diagnosis #Neurology ... Parkinsons #Plus #Syndromes ... #Comparison #Table ... SupraNuclearPalsy #MSA
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
associated with hypokalemia ... overdose) - Sodium ... renal Fanconi syndrome ... #differential #diagnosis ... #nephrology #Causes
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology ... #diagnosis
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Hyponatremia #Algorithm #diagnosis ... #sodium #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Guillain-Barré syndrome ... Hyperreflexia: • Hypocalcemia ... Hyperthyroidism, Serotonin syndrome ... #differential #diagnosis ... #table #neurology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium ... #nephrology
Hypernatremia Classification and Features According to Volume Status - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
Hypernatremia Classification ... hypernatremia - Cushing's syndrome ... #Features #Diagnosis ... #Comparison #Table ... #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Inherited (AR) hypokalemic ... thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Unexplained hypokalemia ... #diagnosis #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... - Compartment syndrome ... per day until stable ... #Differential #Diagnosis ... causes #treatment #nephrology
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