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diagnosis differential algorithm workup acidosis alkaline alp approach arthritis decrease dm2 false hba1c hepatology hgba1c hyophosphatasia hyperferritinemia increase infections infectiousdiseases
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Iron ... • Asplenia Laboratory ... • Hemolytic anemia ... End-stage renal disease
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... #MCV #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
storage form of iron ... Hematologic Malignancy ... Check the iron saturation ... Sideroblastic anemia ... extreme ferritin elevation
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
MCH, MCHC, Serum Iron ... Disease • Marrow ... #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... result in severe anemia ... Mild-to-moderate elevation ... Diagnosis #Workup #Hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Malnutrition • Wilson's disease ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... eliminated • Elevation
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Elevation, Lactic ... presentations and disease ... - assess other laboratory ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
the presence of anemia ... more time for the laboratory ... ferritin level, and iron ... saturation of serum ... Rheumatoid #Arthritis #laboratory
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Growers (Runyon Classification ... Hematologic malignancy ... gastrointestinal symptoms (elevations ... Bone Marrow - Anemia
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