55 results
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
of Chronic Disease ... - Laboratory Testing ... , saturation-worthless ... #Chronic #Disease ... #Laboratory #Testing
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
↓ Transferrin Saturation ... , ↓ Ferritin Anemia ... nl Transferrin Saturation ... ↓ Transferrin Saturation ... differential #hematology #laboratory
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... : IBD, Chronic disease ... #Deficiency #Causes ... differential #diagnosis #anemia ... #nutrition
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... Edema, Celiac disease ... IBD, cancer) #Iron ... #nutrition
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
determine if their anemia ... is secondary to iron ... of chronic disease ... benefit from IV iron ... #Transferrin #Saturation
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... RBC turnover • Iron ... • Asplenia Laboratory ... • Hemolytic anemia ... End-stage renal disease
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
storage form of iron ... absorption of iron ... Iron overload - ... Check the iron saturation ... Sideroblastic anemia
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Deficiency Anemia ... patients with anemia ... • Additional laboratory ... Test for celiac disease ... #Deficiency #Anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Poisoning • Anemia ... Marrow Failure • Anemia ... Diagnosis #Algorithm #Causes
Gastrointestinal Causes of Iron Deficiency Anemia
 • Mass lesions: Carcinoma, Large polyps
 • Inflammatory: Reflux esophagitis,
Gastrointestinal Causes ... of Iron Deficiency ... Anemia • Mass ... sprue, Whipple's disease ... ulcers, Crohn's disease